For me this time it was a bunch of voice memos that had been backed up ages ago, but somehow kept being copied in ….
MacFUSE iPhone Disk now unsupported for lion btw.
Look around with grand perspective or some file visualizer, ssh in and copy over the /Volumes/iPhoneDisk/Recordings contents as backup. I needed to delete that directory (I think). Then sync and ‘other’ was back to a reasonable size (tiny).
Made some fancy playlists that isolate the files with deadlinks, then delete them re-sync phone and life is good.